Biomedical Science | Clinical Research
Focused on disease mechanisms & therapeutic hypotheses
Jimmy Alexis
Aspiring clinical and biomedical researcher specializing in
Alzheimer’s disease, Type 2 Diabetes Mellitus, and tumor biology.
Passionate about hypothesis-driven exploration of complex diseases and translational pathways toward safer, targeted interventions.
Research Focus
Hypothesis-driven exploration of complex disease systems
Neurodegeneration – Alzheimer’s pathology & neuronal survival
Metabolic Disease – Type 2 Diabetes & pancreatic regulation
Tumor Microenvironment – targeted non-toxic delivery concepts
Clinical Translation – from conceptual models to testable strategies
From a scientific standpoint, my independent work centers on understanding how
cellular dysregulation, metabolic disturbance, and microenvironmental signaling
converge to drive complex diseases. I am particularly interested in generating mechanistic,
hypothesis-based models that could inform future therapeutic directions—whether by
stabilizing neuronal networks in Alzheimer’s disease, supporting pancreatic function in Type 2 Diabetes,
or designing conceptual frameworks for tumor-targeted, non-toxic delivery strategies.
Independent Research Projects
Conceptual and literature-based biomedical inquiries
Alzheimer’s Disease – Neuronal Degeneration & Hypothetical Reversal Pathways
Neurodegeneration & synaptic resilience
Literature-driven exploration of amyloid accumulation, tau pathology,
neuroinflammation, and synaptic failure in Alzheimer’s disease, with a focus on
multi-target, hypothetical strategies for restoring neuronal stability and functional connectivity.
Type 2 Diabetes Mellitus – Pancreatic Support & Glucose Homeostasis Concepts
Metabolic regulation & β-cell support
Investigation of insulin resistance, β-cell stress, and inflammatory mediators in
Type 2 Diabetes, leading to a hypothesized, multi-compound strategy aimed at supporting
pancreatic function and stabilizing systemic glucose levels.
Tumor-Based Cancers – Non-Toxic Targeted Delivery Concepts
Tumor microenvironment & selective targeting
Ongoing conceptual research into how tumor vasculature, receptor expression, and
local microenvironmental features could be leveraged to deliver non-toxic payloads
selectively to tumor regions, minimizing systemic exposure while increasing local impact.
Future Directions – Integrating Clinical Observation with Mechanistic Hypotheses
Bridge between bedside & bench
Drawing from direct clinical exposure in ICU, cardiothoracic, and neurocognitive
settings, this line of work aims to generate clinically grounded questions that
can be translated into testable biomedical hypotheses.